NAD+ Therapy in Livonia

What is NAD+?

NAD+ stands for nicotinamide adenine dinucleotide. It is a coenzyme, meaning it is a helper molecule that other reactions cannot run without, and it is present in every cell you have.

Its main job is carrying electrons. The chemistry that converts food into ATP, the molecule your cells actually spend as energy, depends on NAD+ picking up electrons in one reaction and dropping them off in another, cycling between its oxidized and reduced forms thousands of times a second. Without enough of it, that production line slows down.

NAD+ is also a consumable substrate for two families of enzymes that matter for how cells age: sirtuins, which regulate gene expression and metabolic stress responses, and PARPs, which repair damaged DNA. Every time those enzymes work, they use up NAD+ rather than recycling it.

Why do people say NAD+ declines with age?

Because measurements in tissue suggest it does. Studies across several tissue types have found lower NAD+ concentrations in older animals and older people than in younger ones, and the leading explanations are a fall in the enzyme that recycles NAD+ and a rise in the demand placed on it by DNA damage and inflammation.

That decline is well documented as an observation. What follows from it is where the honesty has to start.

Does NAD+ therapy work?

The mechanism is solid science. The clinical benefit in healthy people is not yet established, and you should be skeptical of anyone who tells you otherwise.

What the research currently supports:

• NAD+ is essential. That is settled biochemistry, not a claim.
• Levels fall with age. Observed repeatedly in tissue studies.
• Precursors raise blood NAD+. Human trials of nicotinamide riboside and nicotinamide mononucleotide have shown that supplementation increases measurable NAD+ levels, and that it is generally well tolerated at studied doses.

What the research does not yet support:

• That raising NAD+ reverses aging, restores cognition, cures fatigue, or treats addiction. Trials in humans have mostly been small, short, and focused on safety and blood levels rather than on outcomes people care about.
• That intravenous or injected NAD+ outperforms oral precursors. This has not been demonstrated in good human trials.

So the accurate framing is this: NAD+ therapy is a wellness service with a plausible mechanism and early evidence, not a proven treatment for any condition. Serenity offers it on those terms and will tell you the same thing at the desk.

Why is fatigue worth investigating first?

Because tiredness has causes that are findable and fixable, and skipping the search is the expensive mistake.

Anemia, thyroid disease, vitamin B12 or vitamin D deficiency, poorly controlled blood sugar, sleep apnea, depression, and medication side effects all present as persistent fatigue, and most of them show up on ordinary blood work. Serenity has a lab on site, so that search takes one visit.

If those come back clear and you still want to try NAD+, that is a reasonable, informed choice. Making it the first move instead of the last one is not.

How is it given, and what does it cost?

At Serenity, NAD+ is a $129 push, given on its own or added to any drip on the wellness menu. That price is from the clinic’s own printed menu and is confirmed at the desk before your session.

Sessions are booked rather than walked in, and the times on offer differ from day to day, so the booking page is where you will see them rather than assuming the door being open means the chair is free.

A provider reviews your history and current medications first, goes over what NAD+ can and cannot be expected to do, and answers questions about how often it would be repeated.

People who receive NAD+ commonly report flushing, nausea, or a tight sensation in the chest when it is given too quickly, which is why the rate is controlled and why you are monitored during the session rather than left alone with it.

Who should not have it?

Tell the provider if you are pregnant or breastfeeding, if you have kidney or liver disease, if you have a heart condition, or if you take any regular medication. NAD+ therapy is not appropriate for everyone, and the assessment is the point of the consultation.

If your symptoms are new, worsening, or severe, that is a reason to be examined rather than infused. Walk in seven days a week and a provider will look at what is actually going on.

How do I start?

Book online or call the clinic. NAD+ sessions are scheduled rather than walk-in, so the time is set aside for you, and the booking page shows which times are free on the day you want.